Right choice is (c) Oestrogens
The explanation is: Enzyme catalyzed reactions could be performed in organic solvents other than water, as it is not the ideal medium for the majority of organic reactions. Reactants such as molecular oxygen, steroids, lipids, etc., are more soluble in organic solvents than in water. Some products such as oestrogen may be labile in an aqueous environment. To overcome this, non-aqueous media which allows a much increased volumetric activity to be achieved may be used.