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Inhibition of invertase by sucrose falls into which category of inhibition?

(a) Substrate inhibition

(b) Non-competitive inhibition

(c) Product inhibition

(d) Competitive inhibition

I have been asked this question in final exam.

Origin of the question is Fundamentals topic in division Enzyme Kinetics Fundamentals of Enzyme Technology

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Right choice is (a) Substrate inhibition

The explanation: Invertase inhibition by sucrose is kind of substrate inhibition. It is a special case of uncompetitive inhibition which occurs at high substrate concentrations. Product inhibition is case of competitive inhibition wherein the substrate and the inhibitor have structural similarity. Competitive inhibition is one wherein the substrate and the inhibitor compete for the active site of the enzyme. Non-competitive inhibition occurs when the inhibitor binds at the site away from the binding site, causing a reduction in catalytic activity.

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