Question

Sometimes successive rounds of screening of a genomic library are carried out and an ordered collection of clones is done in a linear fashion, then the process is called as ___________

(a) chromosome jumping

(b) chromosome sorting

(c) chromosome walking

(d) transposon tagging

This question was addressed to me during an interview.

My query is from Database Screening and Screening by Nucleic Acid Hybridisation in chapter Screening Libraries of Genetic Engineering

Answer 1

The correct option is (c) chromosome walking

To explain: Chromosome walking is the process of successive rounds of screening of a genomic library and it leads to the collection of clones in a linear order.