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Lon protease is used for degradation of foreign proteins in E.coli cells. It is active against which type of proteins?

(a) Partially denatured proteins

(b) Completely denatured proteins

(c) Both partially and completely denatured proteins

(d) Intact proteins

I have been asked this question in an online interview.

Enquiry is from Co-expression of Proteins and Optimization topic in division Use of Cloned DNA of Genetic Engineering

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Best answer
The correct choice is (c) Both partially and completely denatured proteins

Easy explanation: Lon protease is used for degradation of foreign proteins. It is active against both partially and completely denatured proteins.

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