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Why is S-dealkylation not observed?

(a) Greater inclination for oxidation of Sulphur

(b) Lesser inclination for oxidation of Sulphur

(c) Lesser inclination for reduction of Sulphur

(d) Greater inclination for reduction of Sulphur

The question was posed to me by my school teacher while I was bunking the class.

Query is from Microbial Transformations of Pesticides in portion Microbial Transformations of Pesticides of Environmental Biotechnology

1 Answer

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Correct answer is (a) Greater inclination for oxidation of Sulphur

The explanation is: S-dealkylation is usually not observed due to greater inclination for oxidation of Sulphur. Sulphur has higher chances to oxidation to form sulphone or sulphoxide. These are nonspecific oxidation reactions; hence, it requires various hydrogen donors. Hence, lesser inclination for oxidation of Sulphur, lesser inclination for reduction of Sulphur, greater inclination for reduction of Sulphur is usually not the case for S-dealkylation.

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