Question

What should be the MOE after extrapolation to humans to be considered as a low risk?

(a) Over 20

(b) Over 30

(c) Over 40

(d) Over 10

The question was posed to me during an internship interview.

This interesting question is from Risk Characterization in division Risk Assessment of Hazardous Waste Management

Answer 1

The correct answer is (d) Over 10

The best I can explain: The Risk of exposure for non-oncogenic effects is expressed as a Margin of Exposure (MOE). If it’s over 10, No Effects Level is a lot higher than the actual exposure occurring among the most exposed individuals within the target population.